Glen Pyle: Association Between Premature Menopause and Coronary Heart Disease Risk
Glen Pyle, Professor, Member of Women’s Health Research Institute (WHRI) and of IMPART, shared a post on LinkedIn about a recent article by Priya M. Freaney et al. published in JAMA Cardiology:
“Menopause increases women’s cardiovascular disease risk and women who experience menopause before age 40 have an even higher risk.
A new study in JAMA Cardiology investigated the connection between premature menopause and coronary heart disease, and found Black women were threefold more likely than White women to enter menopause before age 40 (15.5% vs 4.8%).
The risk of coronary heart disease in these women was 40% higher than women who entered menopause after age 40, regardless of racial background.
Earlier studies have demonstrated a link between early (<45 years of age) and premature (<40 years of age) menopause with coronary heart disease within 7 years of menopause.
This study looked at a significantly longer window of risk (~30 years) and shows that the elevated risk persists.
While menopause is typically seen as a ‘reproductive’ issue best dealt with by gynecology professionals, this study by Priya M. Freaney and colleagues underscores the need for women, family physicians, and cardiologists to consider reproductive history in assessing cardiovascular disease risk.
Clear communication about patient history, risk factors, and strategies to mitigate cardiovascular risks are critical for ensuring a long and healthy life for women.”
Title: Premature Menopause and Lifetime Risk of Coronary Heart Disease
Authors: Priya M. Freaney, Hongyan Ning, Mercedes Carnethon, John T. Wilkins, Norrina B. Allen, Donald M. Lloyd-Jones, Sadiya S. Khan
Read the Full Article on JAMA Cardiology

Stay updated on all scientific advances with Hemostasis Today.
-
May 9, 2026, 16:38Joseph R. Shaw: Risk Stratification is Only Useful if It is Practical, Consistent, and Easy to Apply at the Bedside
-
May 9, 2026, 16:11Milad Abdalla: When 180,000 Becomes 45,000 – The EDTA Trap
-
May 9, 2026, 16:10Gertrud U. Rey: Describing the Mechanism That Causes VITT
-
May 9, 2026, 16:09Dima Shulkin: The Earliest Warning Sign of a Severe Heart Attack May Already Be in the CBC
-
May 9, 2026, 16:08Luisanna M. Sánchez: Selected for the ASH Clinical Research Training Institute
-
May 9, 2026, 16:07Maha Othman: Key Highlights from Southern Ontario Reproductive Biology
-
May 9, 2026, 15:36Rami Z. Morsi: Advancing the Full Spectrum of Stroke Care at UCM 2026 3rd Annual Stroke Symposium
-
May 9, 2026, 15:34Recognizing the Essential Role of Psychosocial Care within Bleeding Disorders Care – EAHAD
-
May 9, 2026, 15:27Abdulrahman Nasiri: How AI and Deep Learning May Help Reshape the Future of Thalassaemia Care