Irma Bagdoniene։ Why Intensive Prevention is the Most Rational Strategy in Preventive Cardiology
Irma Bagdoniene, Cardiologist Specializing in Prevention & Lipidology, shared on LinkedIn about a recent article by Jennifer G. Robinson et al, published in Journal of the American Heart Association:
”Is early, intensive prevention ‘aggressive’? It’s not. On World Logic Day, it just makes sense.
I often tell my patients:
The human body follows simple logic.
In preventive cardiology, clinical inertia is a common barrier. But the evidence to avoid delays is overwhelming. This is the basis of our ‘strike early, strike strong’ strategy:
- The logic of time: Atherosclerosis results from cumulative exposure. It’s the total LDL burden over decades—the “mg-years”—that defines risk. The sooner we act, the more years we protect.
- The logic of causality: LDL cholesterol is a proven causal factor in ASCVD. Mendelian randomization studies and large clinical trials consistently confirm this. Lowering LDL prevents downstream events.
- The logic of measurement: We cannot manage what we don’t detect. Risk scores alone fall short. Advanced assessments like CACS, CCTA, Lp(a), and ApoB provide clear evidence of subclinical disease—calling for early intervention.
The conclusion is simple. The evidence and tools are ready. Early application is the most rational approach to stopping heart attacks before they occur.
Prevention is not aggressive—it is the sensible choice.
On World Logic Day (Jan 14), proclaimed by UNESCO, a reminder:
Good medicine is often just good logic!”
Title: Eradicating the Burden of Atherosclerotic Cardiovascular Disease by Lowering Apolipoprotein B Lipoproteins Earlier in Life
Authors: Jennifer G. Robinson, Kevin Jon Williams, Samuel Gidding, Jan Borén, Ira Tabas, Edward A. Fisher, Chris Packard, Michael Pencina, Zahi A. Fayad, Venkatesh Mani, Kerry Anne Rye, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Pamela S. Douglas, Stephen J. Nicholls, Neha Pagidipati, Allan Sniderman
Read the Full Article on Journal of the American Heart Association․
Stay updated on all scientific advances with Hemostasis Today.
-
Jun 26, 2026, 18:28Daniel Pereira Monteiro: Why Is Beta Thalassaemia Major so Severe?
-
Jun 26, 2026, 18:27Pradip Pawar: Cell and Gene Therapy – Transforming Medicine in the 21st Century
-
Jun 26, 2026, 18:26Aviva Schwartz: How Can We Better Protect Patients After an Ischemic Stroke?
-
Jun 26, 2026, 18:25Does Reversing Factor Xa Inhibitors Really Carry as Much Thrombotic Risk as We Think? – RPTH Journal
-
Jun 26, 2026, 18:25Akshat Jain: Novel Therapies in Childhood Blood and Cancer Disorders
-
Jun 26, 2026, 16:57Abdul Muqtadir Abbasi: Anticoagulation in DVT Patients With Hidden Varices Requires Extreme Caution
-
Jun 26, 2026, 16:42Anesa Mulabecirovic: Why Von Willebrand Disease Takes Years to Diagnose in Women
-
Jun 26, 2026, 16:32Kaitlin Lichty: A New Identity Reflecting a Shared Legacy of Bleeding Disorders
-
Jun 26, 2026, 16:07Toong Youttananukorn: The WFH Registry Driving Better Care and Advocacy