Piezo1 Gain-of-Function Mutation Explains Thromboembolic Complications in Hereditary Xerocytosis – JTH
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Christilla Bachelot-Loza et al, adding:
”Piezo1 gain of function induces a platelet preactivation state
Piezo1 gain-of-function mutations create a platelet preactivation state that enhances thrombosis risk, explaining thromboembolic complications in hereditary xerocytosis patients and revealing mechanosensitive ion channels as critical regulators of platelet hemostatic function.”
Title: Piezo1 gain of function induces a platelet preactivation state
Authors: Christilla Bachelot-Loza, Aurore Marchelli, Laurie Ruch, Divina El Hamaoui, Julien Demagny, Bruna Salau Grau, Clarisse Mouriaux, Wafa Amara, Anaïs Mehl, Emma Ziessel, Shaymaa Alhabib, My Ngoc Ha, Fatima Zemali, Sophie Gandrille, Véronique Picard, Pierre Mangin, Régis Bobe, Loïc Garçon, Catherine Léon, Pascale Gaussem
Read the Full Article on Journal of Thrombosis and Haemostasis.
Stay updated on all scientific advances with Hemostasis Today.
-
Feb 17, 2026, 15:20Giulia Simini: MATRON Study Selected as Top-Scoring Abstract at the BSH Annual Scientific Meeting
-
Feb 17, 2026, 15:082026 NLA Clinical Consensus: Updated LDL and ApoB Targets in Familial Hypercholesterolemia
-
Feb 17, 2026, 14:56Mohamed Sikkander Abdul Razak: Three Days in Nature and Long-Lasting Immune Benefits
-
Feb 17, 2026, 14:46Bartosz Hudzik: Better Control, Similar Tolerability With Quadruple Therapy in Resistant Hypertension
-
Feb 17, 2026, 14:33Richard Keller: Efficacy and Safety of Enlicitide in High-Risk ASCVD Patients
-
Feb 17, 2026, 14:32Flora Peyvandi: Population Pharmacokinetics to Guide Tailored Surgical Dosing in Von Willebrand Disease
-
Feb 17, 2026, 13:54Wolfgang Miesbach: 43-Year Study Links Black Coffee to Reduced Dementia Risk
-
Feb 17, 2026, 09:04Mahesan Subramaniam: A Heart Attack Is a Long Story That Ends Fast
-
Feb 16, 2026, 15:44Lakmali Silva: Silva Lab Showcases Research at the Gordon Research Conference on Plasminogen and Extracellular Proteolysis