Lama Samia: Biochemical Cascade of Myocardial Infarction
Lama Samia, Medical Image Classification and Imaging Researcher at Biomedical Optics and Ultrasound Laboratory (BOUL) Toronto, Canada shared a post on LinkedIn:
“Biochemistry behind a heart attack
A heart attack (myocardial infarction) isn’t just a ‘blocked artery’- it’s a biochemical cascade inside the heart.
When blood flow stops, cardiomyocytes lose oxygen, which leads to failure of ATP production, which in turn causes ion pumps to collapse, resulting in calcium overload and ultimately leading to cell death.
How do we detect this early?
Lab tests reveal the story:
Key biomarkers:
- Troponin I/T– Released from damaged heart cells. Most sensitive and specific
- CK-MB – Indicates cardiac muscle injury; useful for reinfarction detection.
- Myoglobin– Rises quickly; an early warning signal
- LDH1 – Appears later; confirms MI if patient presents late.
- H-FABP – Early detection of subtle cardiac injury.
Other important markers:
- BNP and NT-proBNP indicate heart strain.
- CRP indicates inflammation.
- Electrolytes (K⁺, Ca²⁺) lead to Assess risk of arrhythmia
Timeline of biomarker release guides diagnosis depending on when the patient arrives!
Heart attacks are time – sensitive emergencies!
Understanding their biochemical footprint helps doctors intervene faster and save lives.”
Stay updated with Hemostasis Today.
-
Apr 15, 2026, 04:52Ulrich Pecks: Personalized Approaches to VTE Prevention in Pregnant Women with Inherited Thrombophilia
-
Apr 15, 2026, 04:06Brenda Pleasant: Insights from the HFA Symposium on Hemophilia Care
-
Apr 15, 2026, 03:43Lexy Halloran: Addressing Diagnostic Inequities in Women with Chronic Conditions
-
Apr 14, 2026, 17:32Denise M.: Surviving Sepsis 2026 – The Upstream Revolution
-
Apr 14, 2026, 17:23Meghanath Yenni։ What’s New in Acute Ischemic Stroke in 2026
-
Apr 14, 2026, 17:11Phil Spinella: What Dose of TXA for Children With Severe Traumatic Bleeding Should You Use?
-
Apr 14, 2026, 17:08Abdulrahman Katib: How Endovascular Stenting Is Transforming the Treatment of Severe PTS
-
Apr 14, 2026, 17:00Anna A. Avagyan: Glad to Be Part of EHA Pediatric Hematology-Oncology Course
-
Apr 14, 2026, 16:58Ney Carter Borges: NLRP3 Inhibition in Atherosclerosis – Early Clinical Signal Beyond Lipids