Moustafa Abdou/LinkedIn
May 13, 2026, 14:33
Moustafa Abdou: Could a Commonly Prescribed Drug Trigger Life-Threatening Hemolysis?
Moustafa Abdou, Author and Founder of AskHematologist.com, shared a post on LinkedIn:
“Could a commonly prescribed drug trigger life-threatening hemolysis in your patient?
G6PD deficiency is one of the most common enzymatic disorders worldwide, yet it continues to be under-recognised in day-to-day clinical practice.
The real challenge is not diagnosis alone, but anticipating and preventing hemolytic triggers, particularly in acute care and oncology settings.
Key clinical insights:
- Oxidative stress from infections or drugs can precipitate acute hemolysis.
- Certain medications, including rasburicase, can lead to severe complications if G6PD deficiency is unrecognised.
- Peripheral blood smear may reveal bite cells and blister cells during hemolytic episodes.
- Enzyme testing can be misleading during acute hemolysis and may require repeat confirmation.
- In this updated article, I summarise the pathophysiology, triggers, diagnostic pitfalls, and practical management considerations for G6PD deficiency:
A practical refresher for clinicians involved in prescribing, acute care, and hematology.”
Other posts featuring Moustafa Abdou on Hemostasis Today.
-
Aug 13, 2026, 18:39Lukas Röthlisberger: Real-World Evidence on Effectiveness and Safety of Rivaroxaban in Children
-
Aug 13, 2026, 18:36Soner Yilmaz: Blood Safety in Türkiye Through More Than 22.5 Million Blood Donations
-
Aug 13, 2026, 18:31Muthukumarasamy Raja: FDA Approval of EZPLAZ Marks a Breakthrough in Emergency Plasma Care
-
Aug 13, 2026, 18:29Peter Zdziarski: Protecting Our Community While Creating a Future Where We Are No Longer Needed
-
Aug 13, 2026, 18:29Morgan E Amos: Thrilled to Receive the Student Research Award From HTRS
-
Aug 13, 2026, 16:38Sheharyar Raza: Plasma Exchange in Multiple Sclerosis
-
Aug 13, 2026, 16:31Juan Manuel Cisneros Carrasco: The True Cost of Blood Donation
-
Aug 13, 2026, 16:25Connie Montgomery: Bridging the Gap Between Patients, Culture and Clinical Trials
-
Aug 13, 2026, 16:16Isabella Presch: A New AI Approach to Protein Engineering