Neda K./LinkedIn
Apr 23, 2026, 16:55
Neda K.: When to Hold Antithrombotics and Use Bridging Therapy in Surgery
Neda K., Clinical Pharmacist, shared a post on LinkedIn:
”Perioperative Management of Antithrombotic: When to Hold Therapy
Perioperative management of antithrombotic therapy is all about balancing bleeding and thrombotic risks. The holding times for each agent are outlined in the image below.
Bridging Therapy: Who Really Needs It?
Indications for bridging when interrupting vitamin K antagonists:
Consider only in high thrombotic risk, such as:
- Mechanical heart valves
- Recent venous thromboembolism (VTE) (less than 3 months)
- Very high-risk atrial fibrillation
How to bridge?
- Discontinue warfarin 5 days before surgery.
- Start LMWH or UFH at therapeutic doses 3 days before surgery.
- Discontinue LMWH 24 hours or UFH 4 to 6 hours before surgery.”
Stay updated with Hemostasis Today.
-
May 13, 2026, 16:41Seema Dawood: When Elevated Platelets Signal a Myeloproliferative Neoplasm
-
May 13, 2026, 16:38Kari Tikkinen: Defining Thromboprophylaxis in MIBC Neoadjuvant Care
-
May 13, 2026, 16:28Nadia Tarhini: Evaluating the Risk of Recurrent Thrombosis in Children with ALL
-
May 13, 2026, 16:01Sifat Jubaira: When Low MCV Meets High Platelets
-
May 13, 2026, 15:58Aktham El-rekaby: Immunothrombosis in Acute Ischaemic Stroke
-
May 13, 2026, 15:49Alison Dougall: Oral Health and Cardiovascular Risk in Bleeding Disorders
-
May 13, 2026, 15:38International Journal of Stroke: Oral Anticoagulants and DOAC–Antiplatelet Therapy Are Associated with Increased Major Bleeding Risk
-
May 13, 2026, 15:19Papa Heme։ Causes of Isolated Prolonged aPTT Without Bleeding
-
May 13, 2026, 15:10Wolfgang Miesbach: Rethinking Bleeding Risk in Anticoagulation