Orton Lungu: Navigating High-Risk Pregnancy in Women Living With Sickle Cell Disease
Orton Lungu, Obstetrics and Gynaecology Resident at Ministry of Health of Zambia, shared on LinkedIn:
”As we comemorated the world Sickle Cell Disease.
This is a serious inherited blood disorder caused by a mutation in the HBB gene, leading to abnormal, sickle-shaped red blood cells that block blood flow and cause severe health complications.
It affects more than 7.74 million people globally, with 515 000 new births, primarily in sub-Saharan Africa, which accounts for nearly 80% of global cases.
How does Sickle Cell Disease affect pregnancy and how does pregnancy affect Sickle Cell Disease?
Sickle Cell Disease affects both the mother’s and foetal or neonatal outcomes.
It is associated with a higher risk of maternal morbidity and mortality.
Higher risk of still birth, prematurity and intra-uterine growth restriction.
Pregnancy in women living with Sickle Cell Disease is a high risk pregnancy and needs closer follow-up.
The dehydration due to Nausea and Vomiting of pregnancy can precipitate or exacerbate vaso-occlusive crises.
Pregnancy is a hypercoagulable state and the dehydration or the pregnancy increases the risk of venous thrombo-embolism.”
Stay updated with Hemostasis Today.
-
Sep 22, 2026, 18:49Abdul Rahman Hamad: Early Action for Better Outcomes in Deep Vein Thrombosis
-
Sep 22, 2026, 18:37Carmine Siniscalchi: Age-Adjusted D-Dimer Cutoffs in DVT Diagnosis
-
Sep 22, 2026, 18:37Stefano Romeo: The Cardiovascular Patient Journey is Still Full of Gaps
-
Sep 22, 2026, 18:11Bharath Kumar V.։ Advancing Safer Anticoagulation for Cancer-Associated Thrombosis
-
Sep 22, 2026, 18:10Fatima Zahra: ASH Released New Guidelines on the Diagnosis of Iron Deficiency
-
Sep 22, 2026, 17:49Nirav Dhanesha: Targeting FXI for Safer Anticoagulation
-
Sep 22, 2026, 17:17Eric Lambert: Intravascular Imaging and the Future of Precision PCI
-
Sep 22, 2026, 16:45Claudiu Stoicescu: Are We Starting Cardiovascular Risk Assessment Too Late?
-
Sep 22, 2026, 16:35Complement – Coagulation Crosstalk in Thrombosis