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Wolfgang Miesbach: Practice-Changing Insights on the Efficacy and Safety of Platelet Transfusions at the EHA-SWG

Wolfgang Miesbach/LinkedIn; Roger Schutgens/ www.emedevents.com

May 1, 2026, 07:50

Wolfgang Miesbach: Practice-Changing Insights on the Efficacy and Safety of Platelet Transfusions at the EHA-SWG

Wolfgang Miesbach, Professor of Medicine at Frankfurt University Hospital, shared a post on LinkedIn:

“Platelet transfusions in inherited platelet disorders – powerful, but never ‘routine’

At the EHA‑SWG Scientific Meeting on Bleeding and Platelet Disorders, Roger Schutgens gave a practice‑changing talk on the efficacy and safety of platelet transfusions:

Platelet transfusions remain an important possibility.

But every unit carries a price:

alloimmunization
refractoriness
TRALI/TACO– particularly critical for younger patients who may need repeated support.

What is striking:

Different societies suggest different platelet thresholds for the same procedures.

Many ‘strong’ recommendations are built on low or very low evidence.

In inherited platelet disorders, where function outweighs count, a single cutoff number is simply not enough.

‘Just give platelets’ is not a strategy.

We need individualized, phenotype‑driven decisions that balance immediate bleeding risk against the long‑term consequences of transfusion.” Wolfgang Miesbach