Arrigo Francesco Giuseppe Cicero: Diagnostic and Prognostic Perspectives of Glycocalyx Disruption in Pregnancy
Arrigo Francesco Giuseppe Cicero, Head and Associate Professor of Human Nutrition at Alma Mater Studiorum – University of Bologna and President at SiNut Official, shared a post on LinkedIn about a recent article he and his colleges co-authored, adding:
“I’m pleased to share our latest publication in Inflammation Research:
‘Biomarkers of endothelial glycocalyx dysfunction in pregnancy: a systematic review of clinical relevance and detection techniques’
In this work, we explored the role of the endothelial glycocalyx as a key regulator of vascular homeostasis and its involvement in pregnancy-related complications such as preeclampsia.
Key insights:
- Glycocalyx disruption is consistently associated with adverse maternal–fetal outcomes
- Circulating biomarkers (e.g., syndecan-1, hyaluronic acid, heparan sulfate) may serve as indicators of endothelial injury
- Emerging imaging techniques could support early detection and risk stratification
These findings highlight the potential of integrating glycocalyx-related biomarkers into clinical practice, opening new perspectives for cardio-obstetric care.”
Title: Biomarkers of endothelial glycocalyx dysfunction in pregnancy: a systematic review of clinical relevance and detection techniques
Authors: Federica Fogacci, Duha Yahya, Jeanine Roeters Van Lennep, Katariina Öörni, Valentina Di Micoli, Francesco De Seta, Cristina Scollo, Claudio Borghi, Arrigo Francesco Giuseppe Cicero
Read the Full Article on Inflammation Research
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