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Inflammatory-Coagulation Cascade Interactions in Trauma-Induced Coagulopathy – JTH
Kyosuke Takahashi/First Author of the Article/LinkedIn
Feb 26, 2026, 14:37

Inflammatory-Coagulation Cascade Interactions in Trauma-Induced Coagulopathy – JTH

Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn, about a recent article by Kyosuke Takahashi et al, adding:

”Hyperfibrinolysis in trauma-induced coagulopathy: exploring the role of inflammatory cytokines

Inflammatory cytokines IL-6, IL-1Ra, and MVP-1 demonstrate distinct temporal dynamics peaking four hours post-admission in severely injured patients with hyperfibrinolysis, revealing critical inflammatory-coagulation cascade interactions in trauma-induced coagulopathy.”

Title: Hyperfibrinolysis in trauma-induced coagulopathy: exploring the role of inflammatory cytokines

Authors: Kyosuke Takahashi, Yamakawa Kazuma, Anaar E. Siletz, Morihiro Katsura, John B. Holcomb, Bryan Cotton, Charles Wade, Jessica Cardenas, Matt Martin, Kenji Inaba, Kazuhide Matsushima

Read the Full Article on JTH Journal

Inflammatory-Coagulation Cascade Interactions in Trauma-Induced Coagulopathy - JTH

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Anaar E. Siletz Bryan Cotton Charles Wade Health Hematology Hemostasis Hemostasis News Hemostasis Today Jessica Cardenas John B. Holcomb JTH Kazuhide Matsushima Kenji Inaba Kyosuke Takahashi Matt Martin Medicine Morihiro Katsura thrombosis Yamakawa Kazuma
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