The Results of Landmark COBRRA Trial in Acute VTE Management – ISTH
International Society on Thrombosis and Haemostasis (ISTH) shared a post on LinkedIn about a recent article by Lana Castellucci et al, published in NEJM:
”If you attended ISTH2025, you may have had the chance to hear about the COBRRA trial during our late-breaking research session!
COBRRA is the FIRST head to head trial of apixaban vs rivaroxaban in the management of acute VTE.
We’re thrilled to see that the full study has been published by NEJM Group!
Join us in congratulating Lana Castellucci on this groundbreaking work and read the article.”
Title: Bleeding Risk with Apixaban vs. Rivaroxaban in Acute Venous Thromboembolism
Authors: Lana A. Castellucci, Vivien M. Chen, Michael J. Kovacs, Alejandro Lazo-Langner, Peter Greenstreet, Susan Kahn, Benoit Côté, Sam Schulman, Kerstin de Wit, James Douketis, Deepa Suryanarayan, Tony Wan, Erik Yeo, Genevieve Le Templier, Huyen A. Tran, Abbey Willcox, Helen J. Crowther, Ritam Prasad, Sudeep Shivakumar, Etimbuk Umana, Fionnuala Ni Ainle, Tobias Tritschler, Stefano Barco, Jean-Philippe Galanaud, Marc Blondon, Lisa Baumann Kreuziger, Susan Solymoss, Clive Kearon, Erin Thomas, Tim Ramsay, Gregoire Le Gal, Marc Rodger, for the COBRRA Trial Investigators
Read the Full Article on NEJM

Stay updated on all scientific advances with Hemostasis Today.
-
Apr 23, 2026, 08:16David Ferreira: Identifying the True Drivers of Recurrent Thrombosis
-
Apr 23, 2026, 08:05Hugo Antonio Romo Rubio: Biology, Function, and Updated Classification of von Willebrand Disease
-
Apr 23, 2026, 07:50Hassan Raza: A Smarter Risk Prediction in MPNs Using AI
-
Apr 23, 2026, 05:32Why TXA and rFVIIa Are Not Equivalent in Trauma Bleeding Control – RPTH Journal
-
Apr 23, 2026, 04:08Suraj Mali: Pune Team Initiative for World Hemophilia Day 2026 Advances Early Diagnosis in Hemophilia
-
Apr 23, 2026, 03:58Adam Ho: What Does It Actually Mean to ”Prevent” a Stroke?
-
Apr 23, 2026, 03:49Jakob Krebs Christensen: Mobile Stroke Units Bring Imaging and Treatment Directly to the Patient
-
Apr 23, 2026, 03:30Kimberly Waddell: Mismatch in Post-Stroke Discharge Decisions Impacts Long-Term Recovery
-
Apr 23, 2026, 03:18Pablo Corral: Key Take‑Home Messages on Familial Hypercholesterolemia