Dr Zahoor: DVT Can Lead to PE if The Clot Dislodges
Dr Zahoor, Senior Medical epidemiologist at National institute of health Islamabad, shared a post on LinkedIn:
“Deep Vein Thrombosis (DVT) and Cellulitis, including causes, symptoms, diagnosis, and management:
1. Deep Vein Thrombosis (DVT)
Definition:
DVT is the formation of a blood clot (thrombus) in a deep vein, usually in the legs. It can lead to pulmonary embolism (PE) if the clot dislodges.
Causes / Risk Factors (Virchow’s Triad)
1. Venous stasis: Immobility, long flights, bed rest, surgery
2. Endothelial injury: Trauma, surgery, intravenous catheters
3. Hypercoagulability: Cancer, pregnancy, oral contraceptives, genetic clotting disorders
Symptoms
Swelling in one leg
Pain or tenderness (usually in calf)
Warmth and redness over affected area
Sometimes asymptomatic
Diagnosis
Clinical assessment: Wells score
D-dimer: Elevated in clot formation
Doppler ultrasound: Confirms presence of clot
Venography: Rarely used
Treatment
Anticoagulation: Heparin (UFH or LMWH), then warfarin or DOACS
Compression stockings: Reduce swelling and prevent post-thrombotic syndrome
Thrombolysis / thrombectomy: In severe or extensive.”

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