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Filippo Mazzi: IVIG as an Alternative Therapy for Acute Chest Syndrome in Patients with Sickle Cell Disease
Mar 9, 2026, 15:50

Filippo Mazzi: IVIG as an Alternative Therapy for Acute Chest Syndrome in Patients with Sickle Cell Disease

Filippo Mazzi, Medical Doctor at Integrated University Hospital of Verona, Italy, shared a post on LinkedIn about a recent article he and his colleagues co-authored, adding:

“Excited to share our latest publication in Haematologica.

What can we do when a life-saving treatment is not an option?

We report two challenging cases of acute chest syndrome in patients with sickle cell disease who could not receive blood transfusions for religious reasons. We explored the use of intravenous immunoglobulins (IVIG) as an alternative therapeutic approach, with encouraging clinical outcomes.

These cases highlight how innovative and flexible treatment strategies can help address complex clinical scenarios in sickle cell disease and drive innovation in patient care.

Grateful to all co-authors and collaborators for this work.”

Title: Intravenous immunoglobulins in the management of acute chest syndrome in two Jehovah’s Witnesses with sickle cell disease

Authors: Francesca Begali, Jacopo Ceolan, Silvia Vitale, Simone Villaboni, Matteo Merlo, Rachele Zamperini, Roberto Bertazzo, Soraia Ribeiro Luz, Filippo Mazzi, Lucia De Franceschi

Read the Full Article on Haematologica.

Filippo Mazzi: IVIG as an Alternative Therapy for Acute Chest Syndrome in Patients with Sickle Cell Disease

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