Francois Roubille: New ESC Consensus on Inflammation in Coronary Syndromes
Francois Roubille, Head of the Intensive Care Unit at University Hospital of Montpellier, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in European Heart Journal, adding:
”New ESC consensus on inflammation in coronary syndromes!
Proud to share our new clinical consensus statement on inflammation in coronary syndromes, published in European Heart Journal: Acute Cardiovascular Care, on behalf of several ESC councils and working groups.
We review how inflammation drives the continuum from chronic coronary syndromes to acute coronary syndromes, integrating mechanisms, biomarkers, imaging, and clinical implications.
Key messages include:
- Inflammation is a modifiable but secondary driver of risk in coronary artery disease.
- High-sensitivity CRP is the most practical biomarker for routine clinical use.
- Inflammation assessment should never delay guideline-directed revascularization and prevention.
- Standard therapies and lifestyle changes already exert meaningful anti-inflammatory effects.
- Low-dose colchicine is currently the only widely implementable anti-inflammatory drug in everyday practice, in carefully selected patients.
Beyond summarizing the evidence, the document provides pragmatic guidance on when, how, and in whom to assess and treat inflammation in real-world clinical practice, emphasizing a holistic, patient-centred approach rather than an ‘inflammation-only’ strategy.
I hope this consensus will help colleagues integrate inflammation into coronary care in a balanced way – bridging mechanistic insights, trial data, and daily decision-making.”
Title: Inflammation in coronary syndromes in clinical practice: a clinical consensus statement of the Association for Acute Cardiovascular Care of the European Society of Cardiology, the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases, the European Society of Cardiology Council on Basic Cardiovascular Science, and the European Society of Cardiology Council for Cardiology Practice
Authors: François Roubille, John Alexander Kharlamov, Max Lenz, Rosalinda Madonna, Clément Delmas, Hannah Schaubroeck, Marco Morosin, Johann Wojta, Christophe Vandenbriele, Mathieu Kerneis, George Lazaros, Paul Evans, Kurt Huber, Christian Hassager, Jason Tarkin, Stephane Heymans, Ruxandra Maria Christodorescu, Gal Tsaban, Massimo Imazio, Alessandro Sionis
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