George Dimitrov: SII and Cancer – What Can This Marker Really Tell Us
George Dimitrov, Assistant Professor at Medical University of Sofia, MUS, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Diseases, adding:
“Our second cardio-oncology collaboration from University Hospital ‘Tsaritsa Yoanna–ISUL’, looking at the systemic immune–inflammation index (SII) in 330 patients with solid malignancies.
Interestingly, SII did not help distinguish patients with cancer-associated thrombosis (AUC 0.515), but higher SII was independently associated with recorded all-cause mortality (OR 1.31 per 1000-unit increase, p equals 0.016).
Perhaps SII is less useful as a thrombosis marker and more reflective of the overall inflammatory burden of cancer.
A nice example of how sometimes the most interesting finding is not the one you set out to find.”
Title: Systemic Immune–Inflammation Index, Thrombotic Status, and Mortality in Patients with Cancer: A Matched Cohort Study
Authors: Bozhidar Krastev, Natalia Spasova, Georgi Dimitrov, Elena Kinova, Assen Goudev
Stay updated with Hemostasis Today.
-
Sep 1, 2026, 18:13Ramsha Batool: Chemotherapy-Induced Anemia Impacts Quality of Life in Breast Cancer
-
Sep 1, 2026, 18:09Natalya Shynhera: Using Anemia to Teach Medical English in Real Clinical Practice
-
Sep 1, 2026, 18:06Wei Du: New Therapeutic Potential for PARP Inhibitors in MLL-Rearranged Leukemia
-
Sep 1, 2026, 18:03Tobias Tichelbäcker: PRAGUE-26 Shows Catheter Lysis Beats Anticoagulation Without Ultrasound
-
Sep 1, 2026, 18:00Baptiste Thibault: My First Publication as First Author on Ionized Calcium Monitoring Before Citrate-CRRT
-
Sep 1, 2026, 17:51Nadezhda Vasilyeva: Shifting the Boundaries of Acute Ischemic Stroke Management
-
Sep 1, 2026, 17:49Malik Ghannam: Recent Venous Thrombosis Risk Factors May Help Explain Cryptogenic Stroke in Young Adults
-
Sep 1, 2026, 17:42Rishabh Jain: Renal Artery FMD Is Managed With Balloon Angioplasty Alone
-
Sep 1, 2026, 17:42Caitlin R: The Brain’s Need to Find Patterns