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Jan Sloves: Pelvic Venous Disorder Is Not a Single Syndrome
Jan Sloves/LinkedIn
Jan 16, 2026, 22:01

Jan Sloves: Pelvic Venous Disorder Is Not a Single Syndrome

Jan Sloves, President and Consultant at Vascular Imaging Professionals LLC, shared on LinkedIn:

”Pelvic venous disorder (PeVD) is not a single syndrome but a spectrum of abdominopelvic venous obstruction and reflux; labels like “pelvic congestion,” “nutcracker,” and “May–Thurner” often obscure the underlying hemodynamics.

Fabio H Rossi and Antonia M. Kambara from Brazil propose a protocol that always starts with phenotype and mapping: chronic pelvic pain (CPP), C3–C6 CVD, renal‑vein symptoms, or varicocele prompt Duplex and CT venography of iliac, renal, gonadal, and internal iliac veins, with IVUS confirmation. Treatment is then tailored rather than “embolization‑by-default.”

Key insight: isolated primary gonadal reflux was uncommon (12.3%), whereas isolated iliac obstruction was seen in 36.9% and more than half the cohort had C3–C6 disease, highlighting outflow obstruction as a major driver of PeVD.

Reflecting this, 53.4% of 146 patients were ultimately treated with iliac stents, versus 30.8% with ovarian embolization, 11.7% spermatic embolization, and 4.1% renal stents.

The therapeutic algorithm is simple and provocative:
•Isolated CPP or varicocele with documented reflux → gonadal/pelvic embolization.
•CPP plus C3–C6 CVD and iliac obstruction → iliac stenting first.
•CPP plus flank pain, hematuria, or proteinuria with LRV obstruction → renal vein stenting first, without routine gonadal embolization.

Across all strategies, mean VAS scores fell from ≈8–9 to ≈2–3 and SF‑36 scores roughly doubled over a mean 110‑month follow‑up, with only two minor, asymptomatic gonadal vein bleeds and day‑case care throughout.

Reinterventions were modest (≈10–16%, 0% for varicocele), mostly within 12–18 months, and usually for residual pelvic reflux rather than stent failure.

For vascular teams, the message is clear: systematically look for PeVD in advanced CVD and atypical/recurrent varices, correct iliac or renal outflow first when those phenotypes are present, and reserve pelvic embolization for truly reflux‑dominant disease.

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Read the full article here.

Article: Paradigm shift and long-term results in the diagnosis and treatment of pelvic venous disorder

Authors: Fabio Henrique Rossi, Antonio Massamitsu Kambara

Jan Sloves: Pelvic Venous Disorder Is Not a Single Syndrome

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Antonio Massamitsu Kambara CT CVD Fabio Henrique Rossi gonadal reflux Health Hematology Hemostasis Hemostasis News Hemostasis Today IVUS Jan Sloves Medicine PeVD thrombosis Venography
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