Maria Meritxell Roca Mora: DOACs Show Promise Over VKAs in Kidney Transplant Recipients
Meta Analysis Academy shared on X:
”New Meta Master Publication Alert
A systematic review and Meta-Analysis of 5 studies (n=959 patients) compared direct-acting oral anticoagulants (DOACs) vs. vitamin K antagonists (VKAs) in kidney transplant recipients (KTRs).
Key findings:
- DOACs reduced major bleeding
- DOACs lowered mortality
- No significant difference in VTE risk, in graft failure and kidney function (eGFR)
Conclusion: DOACs may be an effective anticoagulation strategy in KTRs, offering reduced bleeding and mortality compared with VKAs, though evidence quality remains low-to-moderate.”
Read the full article here.
Article: Safety and efficacy of direct oral anticoagulants in kidney transplant recipients: A systematic review and meta-analysis
Authors: Maria Meritxell Roca Mora, Andre Milani Reis, Filipe Piazzi Tavares, Lídia Santos Oliveira, Amanda Godoi, Patricia Viana, Juliano Riella
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