Martha Gulati/www.womenheart.org; Annalisa Filtz, Leandro Slipczuk/LinkedIn
Mar 21, 2026, 11:34
Martha Gulati: How Does Lp(a) Drive Atherosclerosis?
Martha Gulati, Director of the Davis Women Heart Center at Houston Methodist DeBakey Heart and Vascular Center, shared a post on LinkedIn about a recent article she and her colleagues co-authored, adding:
“How does Lp(a) drive atherosclerosis?
- Delivers cholesterol to the arterial wall
- Carries oxidized phospholipids, leading to vascular inflammation
- Interferes with plasminogen, resulting in impaired fibrinolysis
- Promotes an atherothrombotic environment
Understanding these mechanisms strengthens the case for targeted Lp(a) therapies.”
Title: Presumed Mechanisms Underlying Lipoprotein(a)-caused Atherosclerosis
Authors: Annalisa Filtz, Leandro Slipczuk, Martha Gulati
Read the Full Article on ECR Journal.
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