Nicolas Nesseler: Do We Overlook Factor XIII Deficiency in VA-ECMO Patients?
Nicolas Nesseler, Professor at University of Rennes, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Critical Care Journal, adding:
”Do we overlook Factor XIII deficiency in VA-ECMO patients?
We just published a prospective study in Critical Care – 50 patients on VA-ECMO, 413 FXIII measurements.
68percent spent most of their ECMO run with FXIII levels below 70percent. On average, 80percent of their support time in deficiency territory. And none of this is captured by routine PT or aPTT.
No clear trend over time. Huge variability between patients. No proven link with severe bleeding – but our sample size was limited.
The real question now: should we routinely monitor FXIII in these patients, and when does supplementation make sense?
Curious to hear from those managing ECMO patients daily.”
Title: Cumulative exposure to factor XIII deficiency during veno-arterial extracorporeal membrane oxygenation: a prospective cohort study
Authors: Nicolas Nesseler, Adeline Pontis, Erwan Flécher, Mathieu Beaudeau, Nicolas Patou-Parvedy, Isabelle Gouin-Thibault, Alexandre Mansour
Stay updated on all scientific advances with Hemostasis Today.
-
May 25, 2026, 15:47Wadha Al-Muftah: WHO Adopts Landmark Resolution on Precision Medicine
-
May 25, 2026, 15:43Robert Brown: Evidence-Based Management of Obstetric Hemorrhage
-
May 25, 2026, 15:31Tagreed Alkaltham: Beyond the Blood Bank – How Strong Systems Save Lives Before Emergencies Begin
-
May 25, 2026, 15:28Julie Makani: African Health Science Partnerships at INTEREST 2026
-
May 25, 2026, 15:21Michael Stark: How Glucocorticoids in Pregnancy Affect Fetal Development and Why It Matters
-
May 25, 2026, 15:01Abdirahman K. Mohamud: A New Continental Plan for Sickle Cell Disease in Africa
-
May 25, 2026, 15:00Tahsim Anwar: Highlighting Transfusion Therapy as a Cornerstone in the Management of SCD Complications
-
May 25, 2026, 14:59Nimesh Patel: Understanding Plasmapheresis – A Clinical Overview
-
May 25, 2026, 14:58Samwel Mikaye: Pathophysiology, Clinical Features and Management of CAD