Niksa Bagheri: Key Shear Regimes and Physics Selection for Continuum Thrombosis Modeling
Niksa Bagheri, Doctoral Researcher at University of Amsterdam, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Applied Sciences, adding:
“The final chapter of my PhD is out.
It asks a question every simulation engineer faces: which physics does a model actually need?
In thrombosis modelling, the answer mainly depends on the flow regime.
I map four shear regimes, from venous stasis to pathological stenosis, to the minimum processes a continuum model must resolve in each.
More physics is not better; the right physics is.
In the arterial regime, at a fixed inlet wall shear rate, varying only the expansion angle downstream of a constriction raised peak near-wall platelet concentration 2.5-fold.
Aggregates followed the recirculation, not the peak shear, consistent with microfluidic measurements.
The tool: a 3D finite-element model in COMSOL Multiphysics coupling Navier–Stokes–Brinkman flow, reactive transport and a level-set interface.”
Proceed to the video attached to the post.
Title: Mapping Computational Thrombosis Modelling to Shear Regimes: An Application to Post-Stenotic Platelet Aggregation
Authors: Niksa Mohammadi Bagheri, Alfons G. Hoekstra, Gábor Závodszky
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