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Noemi Zampatti: Pediatric Celiac Crisis Complicated by Refeeding Syndrome and Proposed Diagnostic Criteria
Noemi Zampatti/ LinkedIn
May 10, 2026, 18:06

Noemi Zampatti: Pediatric Celiac Crisis Complicated by Refeeding Syndrome and Proposed Diagnostic Criteria

Noemi Zampatti, Pediatrics Resident at Giannina Gaslini IRCCS Pediatric Hospital, shared on LinkedIn about a recent article she and her colleagues co-authored, published in Reports (MDPI) adding:

“When celiac disease becomes a life-threatening emergency

Proud to share our recent publication:

‘Celiac Crisis Complicated by Refeeding Syndrome: A Case Report and Pediatric-Adapted Diagnostic Criteria’

In this study, we report the case of a 23-month-old child presenting with an exceptionally severe form of celiac disease, complicated by:

  • Refeeding syndrome
  • Deep vein thrombosis
  • Intussusception
  • Metabolic and nutritional derangement

Although celiac crisis is now considered rare in high-income countries, this case underscores how rapidly pediatric patients can deteriorate, and how challenging diagnosis and management can be in real-world clinical settings.

Key messages from our report:

  • Early recognition of celiac crisis is critical
  • Severe celiac disease may present even with initially low antibody titers
  • Nutritional rehabilitation itself can be hazardous without close biochemical monitoring
  • Complications may be multisystem and rapidly evolving, requiring high clinical vigilance
  • Multidisciplinary management is essential in complex pediatric cases

We also propose pediatric-adapted diagnostic criteria to support earlier recognition and improve standardization in both clinical practice and future research.”

Title: Celiac Crisis Complicated by Refeeding Syndrome: A Case Report and Pediatric-Adapted Diagnostic Criteria

Authors: Noemi Zampatti, Federico Medina, Angela Calvi, Federica Malerba, Marco Crocco

Noemi Zampatti: Pediatric Celiac Crisis Complicated by Refeeding Syndrome and Proposed Diagnostic Criteria

 

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Angela Calvi celiac disease DVT Federica Malerba Federico Medina Health Hematology Hemostasis Hemostasis News Hemostasis Today Marco Crocco Medicine Noemi Zampatti Refeeding Syndrome Reports (MDPI)
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