Pedro Gaspar: The Role of CD4⁺ T Cells in APS
Pedro Gaspar, Co-Chair at International Society on Thrombosis and Haemostasis (ISTH), Medical Doctor at North Lisbon University Hospital Centre, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Autoimmunity Reviews:
“Happy to share our latest review in Autoimmunity Reviews: ‘Dysregulation of helper, regulatory, and follicular CD4⁺ T cells in antiphospholipid syndrome.’
This article provides a comprehensive overview of current evidence supporting the role of CD4⁺ T-cell subsets – including Treg, Tfh, and Tfr cells – in the pathogenesis of antiphospholipid syndrome, highlighting emerging mechanisms and potential therapeutic targets.
A great collaborative effort.
Many thanks to all co-authors.”
Title: Dysregulation of helper, regulatory, and follicular CD4+ T cells in primary antiphospholipid syndrome: Immunopathology and implications for targeted immunomodulatory therapy
Authors: Pedro Gaspar, Filipa Ribeiro, Válter R Fonseca, Vasco C Romão, João E Fonseca, Luis Graca

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