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Professor Erwin Loh: Brain Iron Levels May Signal Alzheimer’s Risk Years Before Symptoms Appear
Oct 2, 2025, 07:38

Professor Erwin Loh: Brain Iron Levels May Signal Alzheimer’s Risk Years Before Symptoms Appear

 

Professor Erwin Loh, President of Royal Australasian College of Medical Administrators, posted on LinkedIn:

”Brain iron levels may signal Alzheimer’s risk years before symptoms appear

A new brain imaging study provides evidence that high levels of iron in certain parts of the brain may signal an increased risk of developing cognitive problems years before symptoms appear.

The study, published in Radiology, found that greater iron accumulation in two brain regions was linked with later development of mild cognitive impairment, a condition that often precedes Alzheimer’s disease.

These findings suggest that brain iron could play a role in the early stages of neurodegeneration and might eventually serve as a tool for identifying people at higher risk for memory decline.

Source in comments.”

Title: Susceptibility MRI Helps Predict Mild Cognitive Impairment Onset and Cognitive Decline in Cognitively Unimpaired Older Adults

Authors: Lin Chen, Anja Soldan, Andreia Faria, Marilyn Albert, Peter C. M. van Zijl, Xu Li

Alzheimer’s risk

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