Satyam Arora: A Key Gap In Standardized Protocols for Pediatric Massive Transfusion
Satyam Arora, Regional Director South East Asia at International Society of Blood Transfusion (ISBT), shared Nita Radhakrishnan‘s post on LinkedIn, adding:
”Happy to share our recent work on managing massive GI and abdominal hemorrhage in children with inherited bleeding disorders.
A key gap we identified is the lack of robust data and standardized protocols for pediatric massive transfusion, especially outside trauma settings.
Evidence in children remains sparse, fragmented, and underreported.
Improving outcomes will require multi-center collaboration, shared registries, and standardized definitions in pediatric transfusion practice.”
Nita Radhakrishnan, Additional Professor and HOD of Pediatric Hematology-Oncology at Post Graduate Institute of Child Health, shared a post on LinkedIn about a recent article she and her colleagues co-authored, adding:
”Massive GI and intra-abdominal hemorrhage in children with inherited bleeding disorders is rare—but life-threatening.
In our 8-year pediatric bleeding disorders experience (n=788), 1.2% developed massive abdominal bleeding. 40% met massive transfusion criteria.
Intra peritoneal bleeds had significant diagnostic delays.
The defining factor was not factor availability — but teamwork:
- Ped Hematology – rapid factor/bypassing therapy, inhibitor detection
- Ped Gastroenterology – timely endoscopy (high diagnostic yield)
- Radiology – early imaging for occult intraperitoneal/pelvic bleeds
- Pathology – inhibitor assays, coagulation work-up
- Transfusion – structured resuscitation and massive transfusion
- Adolescent care – hormonal plus antifibrinolytic strategies in VWD
Massive bleeding is survivable —even in resource-limited settings—when multidisciplinary systems function seamlessly.”
Title: Managing massive gastrointestinal and abdominal haemorrhage in inherited bleeding disorders: experience from a pediatric cohort
Authors: Nita Radhakrishnan, Anuj Singh, Archit Pandharipande, Aditi Tulsiyan, Hari Gaire, Sudipto Bhattacharya, Ravi Shankar, Savitri Singh, Vikas Jain, Umesh Shukla, Upasana Ghosh, Ankit Agrawal, Satyam Arora, Seema Dua, Sangeeta Tripathy
Read the Full Article on International Journal of Hematology
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