Yan Leyfman: Can a Blood Test Reveal which Cells in Your Body are Aging Fastest?
Yan Leyfman, Medical Oncologist, Co-Founder and Executive Director of MedNews Week, Medical Correspondent at OncLive, shared on LinkedIn about a recent article by Daisy Yi Ding et al., published in Nature Medicine, adding:
“Can a blood test reveal which cells in your body are aging fastest?
A landmark study analyzing 7,000 and more plasma proteins from over 60,000 individuals used AI to estimate the biological age of 40 and more different cell types-from neurons and astrocytes to immune cells and skeletal muscle.
Key findings:
- Aging is highly cell-specific, not uniform across the body.
- Accelerated aging signatures predicted future disease risk, including Alzheimer’s disease, ALS, and lung cancer.
- A new polycellular aging score stratified long-term mortality risk over 15 years.
This work moves beyond measuring ‘how old you are’ biologically-it asks which tissues are aging the fastest, opening the door to more personalized disease prevention and precision medicine.
While these biomarkers remain investigational, they represent an exciting step toward earlier detection of age-related disease and individualized healthcare.”
Title: Plasma proteomic signatures of cellular aging predict human disease
Authors:Daisy Yi Ding, Veronica Augustina Bot, Kenneth L. Chen, James W. Groves, Róbert Pálovics, Daisuke Masuda, Amelia Farinas, Hamilton Se-Hwee Oh, Viktoria Wagner, Nannan Lu, Carlos Cruchaga, Alina Isakova, Jonathan M. Schott, Tony Wyss-Coray
Stay updated on all scientific advances with Hemostasis Today.
-
Aug 12, 2026, 10:58Raed Ahmed: New Insights into Severe Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease
-
Aug 12, 2026, 10:27Cliff Oguk: Designing Health AI Around Real-World Clinical Needs
-
Aug 12, 2026, 09:51Orlando Agrippa: Why Promising Sickle Cell Therapies Continue to Fall Short
-
Aug 12, 2026, 09:34Tiffany Hall: Why Hemoglobin Alone Is Not Enough Before Cardiac Surgery
-
Aug 12, 2026, 08:33Craig Clapper: What the Andrea Doria Collision Teaches Us About Safety
-
Aug 12, 2026, 08:16Chengyong Yang: Can Plasma Reveal Cell Specific Signals
-
Aug 12, 2026, 07:49Alan Dursun: Phnom Penh, Cambodia – Part 3 – Turning Partnership into Action
-
Aug 12, 2026, 06:55Alejandro González Veliz: A Good PCI is not Just about Opening the Artery
-
Aug 12, 2026, 06:39Abdulmalik Alnuqydan: Why Do We Transfuse RBCs Less Than 7 Days Old to Newborns?