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Pregnancy and Hereditary Antithrombin Deficiency: New Study Reveals Critical Clearance Peaks at Delivery
Thrombosis Update/X
Jun 15, 2025, 06:52

Pregnancy and Hereditary Antithrombin Deficiency: New Study Reveals Critical Clearance Peaks at Delivery

Thrombosis Update published on its X:

“A new case study in Thrombosis Update  on hereditary antithrombin deficiency (HATD) in pregnancy shows antithrombin clearance increases in the first and third trimesters, peaking around delivery.”

Title: Antithrombin supplementation to prevent venous thromboembolism: A case of hereditary antithrombin deficiency with increased antithrombin clearance during pregnancy and peripartum

Autors: Ayako Kaneda Takeuchi, Tomoaki Oda, Mei Kitamoto , Emiyu Fujiwara, Kenta Kawai, Megumi Narumi, Yoshimasa Horikoshi, Masako Matsumoto, Yukiko Kohmura-Kobayashi, Naomi Furuta-Isomura, Toshiyuki Uchida, Kazunao Suzuki, Naohiro Kanayama, Hiroaki Itoh, Naoaki Tamura.

Pregnancy and Hereditary Antithrombin Deficiency: New Study Reveals Critical Clearance Peaks at Delivery

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Two-Sentence Summary (Analytical):  A newly published case study highlights that antithrombin clearance significantly increases during the first and third trimesters in pregnant women with hereditary antithrombin deficiency (HATD), peaking around the time of delivery. These findings emphasize the need for dynamic monitoring of antithrombin levels throughout pregnancy to prevent thromboembolic complications in this high-risk population.

You can explore more detailed information on Hemostasis Today.

American Society of Hematology American Thrombosis and Hemostasis Network Antithrombin clearance ASH ATIII monitoring Ayako Kaneda Takeuchi Emiyu Fujiwara European Thrombosis & Haemostasis Alliance Hematology Hemostasis Today Hereditary antithrombin deficiency High-risk pregnancy Hiroaki Itoh ISTH Kazunao Suzuki Kenta Kawai Masako Matsumoto Maternal thrombophilia Megumi Narumi Mei Kitamoto Naoaki Tamura Naohiro Kanayama Naomi Furuta-Isomura Peripartum coagulation Pregnancy Thromboembolism risk Thromboprophylaxis Thrombosis in pregnancy Tomoaki Oda Toshiyuki Uchida Yoshimasa Horikoshi Yukiko Kohmura-Kobayashi
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