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Mahesan Subramaniam: Microplastics – Present in More Than 50% of Arterial Plaques Removed During Surgery
Dato Capt. Mahesan Subramaniam/LinkedIn
Nov 20, 2025, 13:46

Mahesan Subramaniam: Microplastics – Present in More Than 50% of Arterial Plaques Removed During Surgery

Dato Capt. Mahesan Subramaniam, Co-Founder United Health Tourism, shared a post on LinkedIn:

“A recent study has revealed that microplastics are present in more than 50% of arterial plaques removed during surgery, potentially contributing to heart disease. Researchers from the University of Campania in Naples analyzed tissue samples from 257 patients who underwent carotid endarterectomy—a procedure to remove fatty deposits from narrowed arteries. They discovered that nearly 60% of the samples contained polyethylene, the most commonly produced plastic, while 12% also had polyvinyl chloride (PVC).

The presence of these microplastics was associated with a 4.5-fold increased risk of stroke, heart attack, or death over a 34-month follow-up period. This suggests that microplastics may play a role in the development of cardiovascular diseases. Laboratory studies have shown that microplastics can cause inflammation, oxidative stress, and scarring in heart cells, which could lead to impaired heart function.

While the study does not establish a direct cause-and-effect relationship, the findings highlight the potential health risks associated with microplastic exposure. As microplastics are found in various environmental sources, including air, water, and food, their impact on human health warrants further investigation.

Mahesan Subramaniam: Microplastics - Present in More Than 50% of Arterial Plaques Removed During Surgery

Title: Microplastics and Nanoplastics in Atheromas and Cardiovascular Events

Authors: Raffaele Marfella, Francesco Prattichizzo, Celestino Sardu, Gianluca Fulgenzi, Laura Graciotti, Tatiana Spadoni, Nunzia D’Onofrio, Lucia Scisciola, Rosalba La Grotta, Chiara Frigé, Valeria Pellegrini, Maurizio Municinò, Mario Siniscalchi, Fabio Spinetti, Gennaro Vigliotti, Carmine Vecchione, Albino Carrizzo, Giulio Accarino, Antonio Squillante, Giuseppe Spaziano, Davida Mirra, Renata Esposito, Simona Altieri, Giovanni Falco, Angelo Fenti, Simona Galoppo, Silvana Canzano, Ferdinando C Sasso, Giulia Matacchione, Fabiola Olivieri, Franca Ferraraccio, Iacopo Panarese, Pasquale Paolisso, Emanuele Barbato, Carmine Lubritto, Maria L Balestrieri, Ciro Mauro, Augusto E Caballero, Sanjay Rajagopalan, Antonio Ceriello, Bruno D’Agostino, Pasquale Iovino, Giuseppe Paolisso

Mahesan Subramaniam: Microplastics - Present in More Than 50% of Arterial Plaques Removed During Surgery

Read full paper here.

Research Paper
DOI: 10.1056/NEJMoa2309822″

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Albino Carrizzo Angelo Fenti Antonio Ceriello Antonio Squillante Atheromas Augusto E Caballero Bruno D'Agostino Carmine Lubritto Carmine Vecchione Celestino Sardu Chiara Frigé Ciro Mauro Davida Mirra Emanuele Barbato Fabio Spinetti Fabiola Olivieri Ferdinando C Sasso Franca Ferraraccio Francesco Prattichizzo Gennaro Vigliotti Gianluca Fulgenzi Giovanni Falco Giulia Matacchione Giulio Accarino Giuseppe Paolisso Giuseppe Spaziano Health Hematology Hemostasis Hemostasis Today Iacopo Panarese Laura Graciotti Lucia Scisciola Maria L Balestrieri Mario Siniscalchi Maurizio Municinò Medicine Microplastics Nanoplastics Nunzia D’Onofrio Pasquale Iovino Pasquale Paolisso Raffaele Marfella Renata Esposito Rosalba La Grotta Sanjay Rajagopalan Silvana Canzano Simona Altieri Simona Galoppo Tatiana Spadoni University of Campania in Naples Valeria Pellegrini
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