Claudio Laudani on Dual Versus Single Antiplatelet Therapy
Claudio Laudani, Cardiovascular Disease Fellow UNICT, Post-Doc Research Scholar UFHealth JAX, shared on LinkedIn:
”Dual antiplatelet therapy (DAPT) has long been the cornerstone of treatment after PCI, but advances in stent technology and pharmacology are reshaping how we balance ischemic protection and bleeding risk.
In this comprehensive review, we examine:
- The pharmacodynamic rationale of DAPT versus single antiplatelet therapy (SAPT), including differences among P2Y12 inhibitors.
- Clinical evidence comparing DAPT and SAPT strategies in chronic coronary syndrome and acute coronary syndrome patients undergoing PCI.
- The evolving role of early DAPT de-escalation and P2Y12 inhibitor monotherapy in optimizing net clinical benefit.
- Practical considerations for tailoring antiplatelet therapy based on individual ischemic and bleeding risk profiles, and areas where evidence remains limited.
Read more in our review article.”
Article: The pharmacology and clinical evidence for the use of dual versus single antiplatelet therapy
Authors: Claudio Laudani, Luis Ortega-Paz, Francesco Franchi, Fabiana Rollini, Ali Zgheib, Georges El Khoury, Maryam Farahmandsadr, Mohmmad Alawajneh, Marco Spagnolo, Giovanni Occhipinti, Davide Capodanno, Dominick J. Angiolillo
Stay updated on all scientific advances with Hemostasis Today.
-
Sep 25, 2026, 09:49Haley Coleman: Volunteering to Support Hemophilia Awareness
-
Sep 25, 2026, 08:55Hitarth Mehta: BHMS Students Gain Practical Exposure to Haemophilia Diagnosis
-
Sep 25, 2026, 07:25Varun Capoor: How Therapeutic Apheresis and Transfusion Medicine Can Complement Clinical Management in SCD
-
Sep 25, 2026, 07:14Manshi Kesharwani: SAK-GQDs Modulate Thrombus Burden and Endothelial Function in Deep Vein Thrombosis
-
Sep 25, 2026, 06:20Farjah Hassan Algahtani: How Can We Better Identify Patients at Risk of Blood Clots after Metabolic and Bariatric Surgery?
-
Sep 25, 2026, 05:59Carla Lewis: Kids Conquering Sickle Disease Joins Nemours Children’s Hospital for 2nd Annual Awareness Event
-
Sep 25, 2026, 05:47Omid Seidizadeh: Evolutionary Constraint and Population Variation Across Coagulation Genes
-
Sep 25, 2026, 05:40Gerald Bertrand: Presenting UMi-NGS Non-Invasive Foetal HPA Genotyping at DGTI 2026
-
Sep 25, 2026, 05:33Urge Congress to support the Sickle Cell Disease Comprehensive Care Act – ASH