Nicolas Gendron: Challenges in Measuring NETs in Clinical Samples
Nicolas Gendron, Research Fellow and Hematologist at Boston Children’s Hospital, shared a post on LinkedIn about a recent article he and his colleagues co-authored, adding:
“Happy to share that our work on NET measurement in clinical samples has just been published online in the RPTH Journal
Neutrophil extracellular traps (NETs) are key players in both arterial and venous thrombosis, but their detection in blood remains challenging.
In this study of patients with critical limb-threatening ischemia and controls:
- NET markers (MPO–DNA complexes) were detectable in serum but not in plasma
- The type of blood sample (serum versus plasma) appears to impact NET measurement.
- Importantly, serum detection may be influenced by coagulation-related processes, a point that should be carefully considered.
This highlights the urgent need for standardization of preanalytical conditions in clinical studies.
Congrats to the team.”
Title: Differential Presence of Neutrophil Extracellular Traps in Serum Versus Plasma of Patients with Critical Limb-Threatening Ischemia
Authors: Nicolas Gendron, Anne Roche, Vanessa Granger, Joseph Emmerich, Olivier Sanchez, Pascale Gaussem, David M. Smadja, Luc de Chaisemartin
Read the Full Article on Research and Practice in Thrombosis and Haemostasis
Other posts featuring Nicolas Gendron on Hemostasis Today.
-
Jun 26, 2026, 18:28Daniel Pereira Monteiro: Why Is Beta Thalassaemia Major so Severe?
-
Jun 26, 2026, 18:27Pradip Pawar: Cell and Gene Therapy – Transforming Medicine in the 21st Century
-
Jun 26, 2026, 18:26Aviva Schwartz: How Can We Better Protect Patients After an Ischemic Stroke?
-
Jun 26, 2026, 18:25Does Reversing Factor Xa Inhibitors Really Carry as Much Thrombotic Risk as We Think? – RPTH Journal
-
Jun 26, 2026, 18:25Akshat Jain: Novel Therapies in Childhood Blood and Cancer Disorders
-
Jun 26, 2026, 16:57Abdul Muqtadir Abbasi: Anticoagulation in DVT Patients With Hidden Varices Requires Extreme Caution
-
Jun 26, 2026, 16:42Anesa Mulabecirovic: Why Von Willebrand Disease Takes Years to Diagnose in Women
-
Jun 26, 2026, 16:32Kaitlin Lichty: A New Identity Reflecting a Shared Legacy of Bleeding Disorders
-
Jun 26, 2026, 16:07Toong Youttananukorn: The WFH Registry Driving Better Care and Advocacy