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Seema Dawood: Clinical and Laboratory Features of Megaloblastic Anemia
Seema Dawood/LinkedIn
Apr 4, 2026, 16:04

Seema Dawood: Clinical and Laboratory Features of Megaloblastic Anemia

Seema Dawood, Medical Laboratory Technologist at The Aga Khan University Hospital, shared a post on Linkedin:

“Megaloblastic Anemia (Folate, Vitamin B12 Deficiency)

Clinical Features

  • Vitamin B12 deficiency: Neurological manifestations due to spinal cord involvement, such as difficulty maintaining posture and paresthesia in hands and feet
  • Folate deficiency: No neurological symptoms.
    Glossitis.

Laboratory Findings

  • Blood smear:
    RBC: Increased MCV, Macro-Ovalocytes.
    WBC: Hypersegmented Neutrophils.
  • Serum Cobalamin: For detection of Vitamin B12 deficiency.
  • Folate level in RBC and serum: For detection of folate deficiency.”

Seema Dawood

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