Nathan Connell: Why Prophylaxis in vWD Has Historically Lagged Behind Established Practice in Hemophilia
Nathan Connell, Clinical Chief of Hematology at Brigham and Women’s Faulkner Hospital, shared a post on Linkedln about a recent article he and his colleagues co-authored, adding:
“I’m pleased to share our recent paper, ‘Prophylaxis for von Willebrand disease: Is it time for parity with established practice in hemophilia A?’ published in Therapeutic Advances in Hematology.
It was a privilege to work on this with Robert Sidonio, Fernando Corrales-Medina, Jill Johnsen, Michelle Sholzberg, and Caroline Malcolmson.
In this review, we examine why prophylaxis in von Willebrand disease has historically lagged behind established practice in hemophilia, despite a substantial bleeding burden in patients with severe and recurrent disease.
We discuss barriers to broader implementation, review emerging clinical evidence supporting prophylactic VWF replacement, and argue that the field is moving toward a more individualized, phenotype-driven approach that may help bring VWD care closer to parity with hemophilia.
Recent prospective data and regulatory progress suggest that prophylaxis should be considered more systematically for appropriately selected patients.
Thank you to Octapharma for supporting the medical writing assistance for this publication.”
Title: Prophylaxis for von Willebrand disease: Is it time for parity with established practice in hemophilia A?
Authors: Robert F. Sidonio Jr., Fernando F. Corrales-Medina, Jill M. Johnsen, Michelle Sholzberg, Caroline Malcolmson, Nathan T. Connell
Read the Full Article on Therapeutic Advances in Hematology
Other posts featuring Nathan Connell on Hemostasis Today.
-
Apr 16, 2026, 05:22Cedric Hermans: A Simple Way to Stay Updated in Haemophilia and von Willebrand Disease
-
Apr 16, 2026, 04:29Vijay Shah: Increasing Value of AI-Based Assessment in Cardiovascular Risk Prediction
-
Apr 16, 2026, 04:13Mysa Saad: Antiplatelets Increase Bleeding Without Reducing VTE in Cancer Patients
-
Apr 16, 2026, 04:11Paolo Zamboni: Enjoy the New Super Articles From Veins and Lymphatics Page Press
-
Apr 16, 2026, 04:03Platelet DGD – A Common But Underdiagnosed Bleeding Disorder – RPTH
-
Apr 16, 2026, 03:51William Wallace: How Vitamin B12 Is Being Absorbed?
-
Apr 16, 2026, 03:36Santagata Davide: Atypical Vascular Events Revealing Underlying Clonal Autoinflammation
-
Apr 16, 2026, 03:35Iron Deficiency in Women During Reproductive Years – ASH
-
Apr 16, 2026, 03:33Abdallah Othman: Overview of Coronary Arterial Anatomy and Its Clinical Implications