Mohammed Elmourtada Abdulgayoom: Exploring Hyperbaric Oxygen Therapy in Sickle Cell Disease
Mohammed Elmourtada Abdulgayoom, Clinical Hematology Specialist at Hamad Medical Corporation, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Hemoglobin, adding։
“I am pleased to share our newly published narrative review in Hemoglobin: Hyperbaric Oxygen Therapy in Sickle Cell Disease: A Narrative Review of Mechanisms, Clinical Applications, and Future Directions.
In this review, we explored the biological rationale and current clinical evidence for hyperbaric oxygen therapy (HBOT) as a potential adjunctive approach in selected complications of sickle cell disease, including vaso-occlusive pain, avascular necrosis, chronic leg ulcers, ophthalmic ischemia, and priapism.
While HBOT may improve tissue oxygenation and potentially reduce ischemia–reperfusion injury, the available evidence remains limited to case reports, small series, and early-phase studies.
Therefore, its role should currently be viewed as investigational and complementary to standard multidisciplinary care, rather than a routine treatment.
Further prospective and controlled studies are needed to define the patients most likely to benefit, optimal treatment protocols, and safety considerations in sickle cell disease.
Grateful to my co-authors for their valuable contributions: Awni Alshurafa, Jamil R Wafi, Tarek Abouzeid, Jaffer Altooq, and Mohamed A. Yassin.”
Title: Hyperbaric Oxygen Therapy in Sickle Cell Disease: A Narrative Review of Mechanisms, Clinical Applications, and Future Directions
Authors: Awni Alshurafa, Mohammed Abdulgayoom, Jamil R Wafi, Tarek Abouzeid, Jaffer Altooq,Mohamed A. Yassin
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