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September, 2026
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Risk of Thrombosis After Stopping Anticoagulation in APS With aPL Negativization -JTH
May 8, 2026, 18:03

Risk of Thrombosis After Stopping Anticoagulation in APS With aPL Negativization -JTH

Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Claire Kelly et al., adding:

”Thrombotic Recurrence After Anticoagulation Cessation in Patients with Antiphospholipid Syndrome and Antiphospholipid Antibody Negativization: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis of 55 APS patients who discontinued anticoagulation following aPL negativization reports a pooled thrombotic recurrence rate of 1.61 per 100 person-years, suggesting that aPL negativization may warrant re-evaluation of long-term anticoagulation necessity in carefully selected low-risk patients.”

Title: Contrary to current guidance, antenatal factor IX levels increase in female carriers of hemophilia B

Authors: Claire Kelly, Janet Cleary, Catriona Keenan, Isabelle Delachapelle, Leona Connolly, Mary Byrne, Mairead O’Donovan, Niamh M. O’Connell, James S. O’Donnell, Kevin Ryan, Michelle Lavin

Risk of Thrombosis After Stopping Anticoagulation in APS With aPL Negativization -JTH

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