Yusra Junaid: Two New Publications in Thrombosis and Cancer Research
Yusra Junaid, Fourth-Year Medical Student at Dow Medical College, shared a post on LinkedIn, about recent articles she and her colleagues co-authored, adding:
“I’m excited to share two of my recent publications.
1.World Journal of Clinical Cases
‘Direct oral anticoagulants vs low-molecular-weight heparins for cancer-associated thromboembolism’
An updated systematic review and meta-analysis comparing DOACs and LMWH for treating cancer-associated thrombosis (CAT) – a major driver of morbidity and mortality in oncology patients.
- DOACs showed comparable protection against venous thromboembolism recurrence and severe bleeding overall versus LMWH
- Apixaban specifically showed a significant reduction in VTE recurrence
- Metastasis status and platelet count emerged as key moderators of bleeding and mortality outcomes
- Findings support a move toward personalized, risk-stratified anticoagulation strategies in cancer care rather than a one-size-fits-all approach.
‘Heterogeneity in proportional cardiovascular co-listing on cancer death certificates in the United States: a national multiple cause-of-death analysis, 1999–2020’
We analyzed 56M plus US death certificates (CDC WONDER, 1999–2020) using a novel Proportional Mortality Ratio (PMR) framework to track cardiovascular disease co-listing on cancer death certificates.
- Cardiovascular co-listing followed a reverse J-shaped pattern across the lifespan – highest in young adults (ages 15–24, PMR 1.83), dipping to a nadir at 55–64 (PMR 0.34), then rising again in older age
- PMRs rose significantly across all adult age groups from 1999–2020, with the steepest climb in the 55–64 bracket (plus 1.69%/year)
- Young-adult elevations were consistently higher among men, metropolitan residents, and Hispanic/Latino decedents
- Leukemia showed the strongest cardiovascular co-listing signal in young adults; colon cancer showed no significant elevation.
Grateful to my co-authors for their valuable contributions to both studies, looking forward to continued collaboration on future research.”
Title: Direct oral anticoagulants vs low-molecular-weight heparins for cancer-associated thromboembolism
Authors: Faseeh Haider, Faizan Ahmed, Yusra Junaid, Maliha Khalid, Areej Dar, Muhammad Arham, Aman Ullah, Saba Aliha, Muhammad Usman Arshad, Khadija Naeem, Muhammad Moseeb Ali Hashim, Najam Gohar, Asha Ricciuti, Vipul Bhanderi, Fawaz Alenezi, Brijesh Patel
Title: Heterogeneity in proportional cardiovascular co-listing on cancer death certificates in the United States: a national multiple cause-of-death analysis, 1999–2020
Authors: Faizan Ahmed, Tehmasp Rehman Mirza, Yusra Junaid, Hassaan Abid, Haris Bin Tahir, Areehah Zafar Masood, Zaima Afzaal, Gabriel Benjamen, Brijesh Patel
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