Maité Mulkers: Time is Brain, and One Reason is That a Thrombus Develops Over Time
Maité Mulkers, PHD Researcher at LMU Klinikum München, shared a post on LinkedIn:
“Time is brain, and one reason is that a thrombus develops over time.
I had the opportunity to comment on the work of Zang and colleagues, describing how blood clots become more stiff and harder to treat within hours and over days.
The culprit?
Serpin B3-positive neutrophils, which upregulate TGF-β1 and promote collagen deposition.
More on this neutrophil-driven remodeling of thrombi, and the potential of Serpin B3 as a therapeutic target and our commentary with Rainer Kaiser.”
Title 1: Pathogenic role of serpin B3-positive neutrophils in reinforcing thrombus stiffening during ischemic stroke
Authors: Jiankun Zang, Aijun Lu, Bing Yang, Na Tan, Qihuan Liu, Liping Wei, Ying Liang, Sijie Zhou, Zefeng Tan, Xiufeng Xin, Shengwen He, Panwen Wu, Yufeng Li, Zhifeng Xu, Xuanlin Su, Hongcheng Mai, Anding Xu, Dan Lu
Read the Full Article on Blood
Title 2: The clot stiffens: neutrophil serpin B3 in ischemic stroke
Authors: Maité Mulkers, Rainer Kaiser
Read the Full Article on Blood
Stay updated on all scientific advances with Hemostasis Today.
-
Nov 13, 2026, 03:21Abdul Muqtadir Abbasi: Iron Deficiency Beyond Anemia and the Importance of Finding the Cause
-
Nov 13, 2026, 03:05Marc Carrier: Aspirin vs Anticoagulants for VTE Prevention After Joint Replacement
-
Nov 13, 2026, 02:28Julia Sjöberg: ROCK1 Inhibition and Red Blood Cell Recovery After Chemotherapy
-
Nov 13, 2026, 02:07Tonie Reincke: Understanding Deep Vein Thrombosis and Vascular Health
-
Nov 13, 2026, 01:52Akshita Singh: The Remarkable Process of Blood Clotting
-
Nov 12, 2026, 22:52Milka Koupenova: The Role of Platelet RIG-I in Regulating Thrombotic Responses
-
Nov 12, 2026, 22:50Arun V J: Why Has India Still Not Achieved 100% Voluntary Blood Donation?
-
Nov 12, 2026, 22:49Sickle Cell Disease Deserves to Be Prioritised in Ghana – ISCC
-
Nov 12, 2026, 22:47Samir Kumar Beura: Delighted to Serve as a Topic Editor for a Research Topic in Frontiers in Neuroscience