ADAMTS13 and Vascular Cognitive Impairment in the Heart–Brain Connection Study – JTH
Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn about a recent article by Amos Pomp et al, adding:
”ADAMTS13 and von Willebrand Factor in relation to vascular cognitive impairment and cerebral small vessel disease: the heart-brain connection study
In 267 participants from the Heart-Brain Connection study, lower ADAMTS13 activity was independently associated with vascular cognitive impairment (OR 1.46 per SD decrease), whereas elevated von Willebrand factor was not.
Both lower ADAMTS13 and higher VWF correlated with markers of cerebral small vessel disease, including white matter hyperintensities and lacunes.’
Title: ADAMTS13 and von Willebrand Factor in relation to vascular cognitive impairment and cerebral small vessel disease: the heart-brain connection study
Authors: Amos Pomp, Mathijs Rosbergen, Moniek de Maat, Paul S. de Vries, Arfan Ikram, Mat Daemen, Imo Hoefer, Wiro Niessen, Jeroen de Bresser, Esther Bron, Charlotte Teunissen, Geert Jan Biessels, Robert van Oostenbrugge, Frank Wolters
Stay updated on all scientific advances with Hemostasis Today.
-
Aug 21, 2026, 17:55Rosna Kerdson: The Role of Plasma in Modern Medicine
-
Aug 21, 2026, 17:41Abdul Mannan: Type 2N VWD Can Wear Haemophilia A’s Lab Coat
-
Aug 21, 2026, 17:33Ursula Porage Dona: How Data Can Strengthen Advocacy for Better Patient Outcomes
-
Aug 21, 2026, 17:18Nandini Pethe: Microhealth Can Be as Simple as Logging Treatments and Bleeds
-
Aug 21, 2026, 15:53Gregory Lim: Nicotine Products and Cardiovascular Risk
-
Aug 21, 2026, 15:26Mariusz Kruk: Plaque-Directed Intervention for the Prevention of Myocardial Infarction
-
Aug 21, 2026, 15:17Leveraging Data to Drive Sustainable Care for Haemophilia and Haemoglobinopathies – NNHF
-
Aug 21, 2026, 15:04Sex Differences in Platelet Function in Type 2 Diabetes – Seminars in Thrombosis and Hemostasis
-
Aug 21, 2026, 15:04Parth Parmar: RBC Morphology – A Practical Guide to Blood Smear Interpretation