Can GDF-15 Predict Bleeding Risk in VTE? – JTH
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Timothy Hoberstorfer et al., adding:
“Growth differentiation factor-15 and bleeding risk in patients with venous thromboembolism
Growth differentiation factor-15 has been proposed as a marker of bleeding risk, but it did not deliver here.
In patients anticoagulated for acute venous thromboembolism, GDF-15 levels showed no association with clinically relevant bleeding and added nothing to existing bleeding prediction.
The result argues against using this biomarker to guide anticoagulation decisions in VTE.”
Title: Growth differentiation factor-15 and bleeding risk in patients with venous thromboembolism
Authors: Timothy Hoberstorfer, Stephan Nopp, Daniel Steiner, Cornelia Englisch, Philip Kienzl, Benedikt Weber, Monika Fritzer-Szekeres, Ingrid Pabinger, Cihan Ay

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