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Tom Van den Hoek: Warburg Effect Mimicking Refractory Shock in Cancer-Associated PE
Tom Van den Hoek/LinkedIn
Sep 5, 2026, 05:38

Tom Van den Hoek: Warburg Effect Mimicking Refractory Shock in Cancer-Associated PE

Tom Van den Hoek, Cardiology Resident at Jessa Ziekenhuis, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in European Heart Journal – Case Reports, adding:

”New Case Report Published.

I am excited to share that our case report, ‘Potential pitfalls in diagnostic and therapeutic decision-making in pulmonary embolism-related obstructive shock in patients with cancer,’ has been published in European Heart Journal – Case Reports.

This case report describes how malignancy-associated metabolic alterations, such as the Warburg effect, can interfere with therapy in acute pulmonary embolism. Awareness of alternative causes of hyperlactatemia is essential to avoid unnecessary invasive interventions and to optimize individualized treatment strategies in cancer-associated PE.

Grateful to my co-authors Peter Kayaert, Philippe Timmermans, and Eva De Caluwe for their collaboration and valuable insights throughout this work.”

Title: Potential pitfalls in diagnostic and therapeutic decision-making in pulmonary embolism-related obstructive shock in patients with cancer: a case report

Authors: Tom Van den Hoek, Peter Kayaert, Eva De Caluwé, Philippe Timmermans

Tom Van den Hoek: Warburg Effect Mimicking Refractory Shock in Cancer-Associated PE

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Eva De Caluwé Health Hematology Hemostasis Hemostasis News Hemostasis Today Medicine obstructive shock Peter Kayaert Philippe Timmermans Pulmonary embolism Tom Van den Hoek Warburg effect
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