Aryabhatta Sadhu: Irradiation of Blood Components – From Clinical Indication to Laboratory Release
Aryabhatta Sadhu, Attending Consultant and Head of Transfusion Medicine at Fortis Hospital Shalimar Bagh, New Delhi, Member of AABB, Member International Society of Blood Transfusion (ISBT), shared a post on LinkedIn:
“Irradiation of blood components: from clinical indication to laboratory release
Preventing transfusion-associated graft-versus-host disease (TA-GVHD) requires timely identification of patients who need irradiated cellular components. Irradiation prevents donor T-lymphocyte proliferation; leukoreduction does not provide equivalent protection.
I have prepared these two infographics as a practical reference for clinicians and transfusion laboratory teams.
The clinical poster addresses indications, component selection and situations in which irradiation is not routinely required. The laboratory poster covers dose requirements, process validation, quality control, traceability, storage restrictions and processing costs.
The material draws on AABB, British Society for Haematology, NHS Blood and Transplant, and WHO resources. American and European requirements are distinguished where they differ, particularly for dose specifications and post-irradiation red-cell storage.
In practice, the challenge extends beyond delivering the prescribed radiation dose. Treatment history must be available, irradiation requirements must remain visible across admissions, and the correct component must reach the patient within its revised expiry.
These summaries are intended to support clinical discussion, staff training and review of institutional irradiation policies. They should be used alongside locally approved protocols and component specifications.”
Other posts featuring Aryabhatta Sadhu on Hemsotasis Today.
-
Oct 21, 2026, 18:13Wolfgang Miesbach: Hereditary Hemorrhagic Telangiectasia An Overlooked Bleeding Disorder
-
Oct 21, 2026, 17:55Gayatri Kotwal։ New Review on Anemia, Pain, and Nutritional Deficiencies in Cancer Patients
-
Oct 21, 2026, 17:40Tetsuzan Ron: Iron Deficiency Without Anemia Clinical Impact and Management
-
Oct 21, 2026, 17:29Amir Hossien Esfandiari։ The Association Between Viral Infections and Aplastic Anemia
-
Oct 21, 2026, 17:16Melissa Hollo: A Meaningful Step Forward for Women’s Health
-
Oct 21, 2026, 17:09Chipili Ng’onga: Have You Ever Seen a Result That Just Didn’t Make Sense?
-
Oct 21, 2026, 16:57Fabrice Cognasse: Celebrating the Next Generation of Platelet Research and Transfusion Medicine
-
Oct 21, 2026, 16:47Christabel Odeta: Treating Pediatric Cancer in Children With Sickle Cell Disease
-
Oct 21, 2026, 16:36Sharlene Haywood: Bringing Multidisciplinary Learning Into Nursing Practice