Maha Othman: ISTH-BAT Reference Ranges Validated Across Five Continents in Children
Maha Othman, Co-Chairman SSC on Disseminated intravascular coagulopathy at International Society on Thrombosis and Haemostasis, shared Journal of Thrombosis and Haemostasis’ post on LinkedIn:
“Delighted to see this important work/supported by International Society on Thrombosis and Haemostasis (ISTH) completed and now published!
Congratulations to the whole team!
Specially our collaborators from across the globe.
This landmark global multicenter study included 1,168 healthy participants from 7 countries across 5 continents, spanning the pediatric age range of 0–18 years, including both males and females and representing diverse healthcare and socioeconomic settings.
These data provide important global validation of the current ISTH-BAT reference range in healthy children and adolescents.
While the overall reference range of 0–2 remains appropriate for individuals under 18 years, the study highlights an important sex-related difference in adolescents: for females aged 12–17 years, a score of 0–3 may be considered within the normal range, interpreted in conjunction with the clinical context.”
Journal of Thrombosis and Haemostasis shared a post on LinkedIn about a recent article by Yousra Tera et al, adding:
“Global multicenter study establishing the reference range for ISTH-BAT bleeding scores in individuals under 18 years: Communication from the SSC of the ISTH
Healthy participants under 18 (n = 1,168) were recruited across 7 countries and 5 continents to validate ISTH-BAT reference ranges.
The overall range of 0–2 held.
A positive age-related trend in scores more than 0 was significant, and among 12–17 year-old females the 2.5th–97.5th percentile extended to 0–3.”
Title: Global multicenter study establishes the reference range for ISTH Bleeding Assessment Tool scores in individuals under 18 years: communication from the SSC of the ISTH
Authors: Yousra Tera, Ryan Babensee, Ahmad Ekhtiar, Ahmad Darwish, Helen Okoye, Margareth C. Ozelo, Mozah Al Marshood, Munira Borhany, Elvira Grandone, Jim Riddel, Margaret L. Rand, Robert Sidonio, Jamie M. O’Sullivan, Ross Baker, Paula James, Maha Othman
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