Nathan Punwani: EASIX and sC5b-9 Predict TMA After Allogeneic Stem Cell Transplantation
Nathan Punwani, Blood and Marrow Transplant Physician at Mayo Clinic, shared a post on X about a recent article by Wenwen Guo et al., published in Bone Marrow Transplantation, adding:
“EASIX score (LDH x Cr/Platelets) and sC5b-9 predicts thrombotic microangiopathy (TMA) after allogeneic stem cell transplant.
Patients with a high baseline EASIX (more than 6) and elevated sC5b9 at day 14 after transplantation have a 32.4% incidence of TMA in the first 100 days after transplant.”
Title: EASIX and sC5b-9 for early identification of adults at high risk of developing TA-TMA after allo-HCT
Authors: Wenwen Guo, Shulian Chen, Xiaoyu Zhang, Mingyue Xu, Xianjing Zhang, Jiali Wang, Yawei Zheng, Yuyan Shen, Qingzhen Liu, Xiaofei Ni, Mengnan Lv, Tingting Zhang, Yuanyuan Shi, Fengjiao Wang, Xiaoli Zhao, Jialin Wei, Rongli Zhang, Xin Chen, Yigeng Cao, Yong Li, Yueyi Mu, Aiming Pang, Mingzhe Han, Guoqing Zhu, Wenbin Cao, Erlie Jiang
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