Michael Baria: Platelet Concentration and PRP Outcomes in Partial Rotator Cuff Tears
Michael Baria, Lead for The Early Osteoarthritis and Joint Health Program at The Ohio State University Wexner Medical Center, Head Team Physician for Ohio State Wrestling at The Ohio State University Department of Athletics, shared a post on LinkedIn about a recent article by Joseph J Lim et al. published in Orthopaedic Journal of Sports Medicine, adding:
”In this meta-analysis of level 1, randomized studies, platelet concentration did not influence outcomes for partial rotator cuff tears.
Basic science has repeatedly shown that worse histopathology is best treated with higher platelets and higher leukocytes.
However, this review shows that we haven’t translated that to clinical care (yet).
High vs low dose (as defined by the authors) didn’t make a difference.
Also, PRP vs no PRP didn’t make a difference.
How do you handle these?
What do you make of these findings?
In our experience, it’s very difficult to design controlled rotator cuff studies for a myriad of reasons.
Tendinopathy isn’t a partial tear.
There are confounding pathologies like AC, biceps, etc.
Finally, our clinical experience has consistently demonstrated that moderate dose (general range of 6-10 B) PRP delivered to the subacromial bursa with proper rehab works well and avoids complications (I.e. frozen shoulder) from intra-tendinous injections.”
Title: Platelet Concentration Is Not Associated With Improved Pain for Partial-Thickness Rotator Cuff Tears Treated With Platelet-Rich Plasma: A Systematic Review and Meta-analysis With Meta-regression of Level 1 Randomized Controlled Trials
Authors: Joseph J Lim, John W Belk, Carson Keeter, Emilea A Stepaniuk, Sophie D Gerber, Jacob F Oeding, Eric C McCarty, Rachel M Frank
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