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November, 2026
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Marc Carrier: Advancing Catheter-Related Thrombosis Prevention Through Factor XI Inhibition
Nov 8, 2026, 12:22

Marc Carrier: Advancing Catheter-Related Thrombosis Prevention Through Factor XI Inhibition

Marc Carrier, Professor at Ottawa Hospital Research Institute, shared a post on LinkedIn about a recent article by Jeffrey Zwicker et al, published in The Lancet Haematology, adding:

“ROXI-CATH: targeting factor XI to prevent catheter-related thrombosis.

Presented at AHA26 and now published in The Lancet Haematology, this phase 2 randomized, double-blind, placebo-controlled trial evaluates amrecibart and cenvacibart for thromboprophylaxis following PICC placement, an important clinical challenge.

Looking forward to seeing how this research advances catheter-related thrombosis prevention.”

Title: Amrecibart and cenvacibart for the prevention of catheter-related thrombosis (ROXI-CATH): a double-blind, randomised, placebo-controlled, phase 2 trial

Authors: Jeffrey Zwicker, Aaron Kithcart, Justin Kaplan, Poulabi Banerjee, Keshini Vyas, Dan Chalothorn, José Raya, Siyu Li, Laura Fredenburgh, Mihaela Mocan, Rosen Razboynikov, Lori Morton, David Gutstein, Kathryn Musgrave, Gregory Piazza

Marc Carrier: Advancing Catheter-Related Thrombosis Prevention Through Factor XI Inhibition

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