Abdul Mannan: A Normal Factor Level Can Still Miss the Story
Abdul Mannan, Consultant Haematologist at Betsi Cadwaladr University Health Board, shared a post on LinkedIn:
“A normal factor level can still miss the story.
That is the false reassurance trap in haemophilia carriers.
The lab result matters. Of course it does. But it should never be used as a permission slip to ignore bleeding symptoms.
Here’s what I want every trainee to remember:
- FVIII and FIX levels are risk clues
- Bleeding history is a clinical signal
- Heavy periods, nosebleeds, oral bleeding, bruising, procedure bleeding, and joint pain all matter
- A structured BAT or HMB screen can change the conversation
- Symptomatic carriers need a documented plan and review
- Haemophilia Carrier Post 1 of 8
One number rarely explains the whole patient.
The better question is not, ‘Is the factor level normal?’
The better question is, ‘Does the bleeding phenotype fit the life this patient is living?’
That small change can stop years of reassurance without action.
What phrase do you use in clinic to move from ‘normal result’ to ‘proper bleeding assessment’?”
More posts from Dr Abdul Mannan on Hemostasis Today.
-
May 17, 2026, 18:50Tony Cambridge: Exploring the Pros and Cons of POCT D-Dimer in Diagnosing DVT
-
May 17, 2026, 18:47Krishna Kumar Dhakchinamoorthi: Artificial Intelligence in Deep Vein Thrombosis
-
May 17, 2026, 18:44Javed Anees: Megaloblastic Anemia – Biochemical Basis and Clinical Approach
-
May 17, 2026, 18:42Kishanlal Munshi: EC Approves Pfizer’s HYMPAVZI for Hemophilia A and B With Inhibitors
-
May 17, 2026, 18:15Shayan Mohammadmoradi: Interesting Global Study with Insightful Points on Women’s Awareness of VTE
-
May 17, 2026, 18:07Mae Galang: Apply for the Position of Rare Blood Disorder Account and Community Manager
-
May 17, 2026, 17:41Wolfgang Miesbach: What Does Acquired Haemophilia A Truly cost, Clinically and Economically?
-
May 17, 2026, 17:35Femi Ogunleye: New PhD Publication on Targeted Thrombolysis
-
May 17, 2026, 16:12Double Your Impact Help Close the Hemophilia Diagnosis Gap and Expand Access to Life Saving Care – WFH