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Ahmed Koriesh: Stroke Primary Prevention – Questions We Hear Every Day

Ahmed Koriesh/LinkedIn

Feb 5, 2026, 16:12

Ahmed Koriesh: Stroke Primary Prevention – Questions We Hear Every Day

Ahmed Koriesh, Director Hospital Neurology Service at Cleveland Clinic Florida, shared on LinkedIn:

“Stroke Primary Prevention – Questions We Hear Every Day

‘My dad is 70 and healthy – should he start aspirin to prevent stroke?’
‘How much exercise do I actually need?’
‘I have diabetes – does my A1c need to be 6.5?’
‘Are GLP-1 drugs really good for stroke prevention?’
‘What exactly is the Mediterranean diet?’

These questions come up daily — in clinic, on rounds, and at the bedside.

Key evidence-based takeaways:

Aspirin is NOT beneficial for primary prevention in adults ≥70
≥150 min/week of moderate activity lowers stroke risk (Moderate means HR increased 50-60%, or in other words, you can talk but not sing)
Intensive glycemic control (A1c ≤6.5%) increase risk of hypoglycemia compared with < 7, with no proven stroke benefits.
Yes, GLP-1 receptor agonists reduce stroke in type 2 diabetes
Mediterranean diet means less red meat, processed food, more sea food, vegetables, whole grains, legumes.

Check out NeuroWiki, the newest educational addition to NeuroTrials.ai — built for neurology residents, fellows, and clinicians.

Primary Stroke Prevention:

Prevention works — but only if we close the knowledge gap.’

Ahmed Koriesh