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Al-Ola A Abdallah on MGUS-Related Bleeding Disorders
Sep 11, 2025, 08:08

Al-Ola A Abdallah on MGUS-Related Bleeding Disorders

Al-Ola A Abdallah, Associate Professor and Director of the Plasma Cell Disorder Program at the University of Kansas Medical Center, has shared a post on X:

“4 bleeding disorders might be associated with MGUS:

  • Acquired von Willebrand disease (AvWD) — paraprotein clears or binds vWF
  • Acquired factor inhibitors (esp. FVIII, rarely FXIII)
  • Dys/hypofibrinogenemia — paraprotein interferes with fibrinogen
  • Platelet dysfunction — coating/inhibition by paraprotein”

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