Alfadil Haroon: New Genetic Insights into Bone Marrow Failure Syndromes
Alfadil Haroon, Assistant Consultant of Hematology at King Faisal Specialist Hospital and Research Centre, Assistant Professor at Alfaisal University, shared a post on LinkedIn:
“Happy to share our book chapter titled ‘Newly Recognized Marrow Failure Syndromes‘ in the textbook on bone marrow failure syndromes.
This chapter reviews recently identified bone marrow failure syndromes described between 2012 and 2025, expanding beyond the classical conditions such as Fanconi anemia and Dyskeratosis congenita.
Advances in Next-Generation Sequencing have enabled the discovery of several novel genetic etiologies, including MYSM1, DNAJC21, ADH5/ALDH2, MECOM, ERCC6L2,TP53,OSM, and SAMD9/SAMD9L.
These findings are reshaping our understanding of inherited BMF, highlighting diverse clinical phenotypes, early onset cytopenias, and variable risks of progression to myeloid malignancies.
Improved genomic insights are helping clinicians refine diagnosis, risk assessment, and treatment strategies.”
Stay updated with Hemostasis Today.
-
Aug 11, 2026, 13:53Steven Lubega: Why Are Healthy Newborns Born Poorly Equipped To Stop Bleeding?
-
Aug 11, 2026, 13:47Why Stroke Risk Changes During Pregnancy – International Journal of Stroke
-
Aug 11, 2026, 13:43Moyahabo Julius Rampya: Shaping the Future of Stroke Care in Africa
-
Aug 11, 2026, 13:34Brett Hoover: Plaque Burden May Be Key to Predicting MACE Risk
-
Aug 11, 2026, 11:47Rucha Patil: Strengthening Evidence-Based Haemophilia Care Across India
-
Aug 11, 2026, 11:38Maria Hadjidemetriou: The Patient Perspective in Thalassemia Care
-
Aug 11, 2026, 11:04Wolfgang Miesbach: The Critical Need for Tailored Dosing in VWD
-
Aug 11, 2026, 08:20Hasan Abbas Zaheer: Strengthening Universal Access to Safe Blood in Pakistan
-
Aug 11, 2026, 08:07Nicola Pozzi: Advancing Hemostasis Through Scientific Collaboration at Hemostasis GRC