Jignesh Patel: Call for Papers on Safer IV Unfractionated Heparin Use
Jignesh Patel, Reader and Honorary Consultant Pharmacist in Anticoagulation at King’s College London, shared a post on LinkedIn:
“Call for papers – improving the safety and efficacy of intravenous unfractionated heparin infusions in clinical practice
Pleased to be co-leading as guest editor with Dr Nienke van Rein a theme issue for the British Journal of Clinical Pharmacology focused on improving the safety and efficacy of intravenous unfractionated heparin infusions in clinical practice.
Unfractionated heparin (UFH) was the first anticoagulant to become available in clinical practice for the prevention and treatment of thrombosis and is included on the WHO list of essential medications as one of the most critical and effective medications necessary to meet the needs of a healthcare system.
However, UFH is a leading cause of anticoagulation related adverse drug events in health systems around the world. UFH is classed as one of six drugs most frequently involved in serious medication events and is classified by the Institute for Safe Medication Practices as a ‘high-alert’ medication.
The aims of this special issue are to:
- Consolidate research and best practice initiatives associated with the use of IV UFH infusions
- Highlight research which addresses dosing and monitoring strategies for IV UFH infusions
- Report on how IV UFH infusion use can be minimised through alternative anticoagulant use, to manage risk
- Describe UFH antidote dosage strategies in specific situations (e.g. bleeding or at the conclusion of cardiopulmonary bypass)
Topics of interest for this call for papers include but are not restricted to the following:
- Anticoagulation stewardship initiatives which improve the safe use of intravenous unfractionated heparin infusions in clinical practice
- Dosing and monitoring issues associated with intravenous unfractionated heparin infusions;
Strategies being utilised to minimise the use of intravenous unfractionated heparin infusions in practice
- Use of AI in the dosing of IV UFH infusions
- The safe integration of IV UFH dosing and monitoring protocols into electronic prescribing systems
- Educational initiatives used to manage IV UFH risks in clinical practice
- Protocol standardisation leading to safer and consistent use of IV UFH infusions
- IV UFH infusion use in special populations (e.g. paediatrics, ecmo, liver cirrhosis, CVVH)
- Monitoring assays for IV UFH infusions
- Point of care testing for IV UFH infusions
- UFH antidote dosage and administration.
Deadline for submissions: Friday, 30 July 2027.”
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