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Riitta Lassila: How APAC Impacts the Interplay Between Complement and Coagulation
Feb 24, 2026, 13:59

Riitta Lassila: How APAC Impacts the Interplay Between Complement and Coagulation

Riitta Lassila, Professor of Coagulation Medicine at University of Helsinki, shared a post on LinkedIn about a recent article she and her colleagues co-authored, adding:

“Our team has published about how the heparin proteoglycan mimic APAC impacts the interplay between complement system and coagulation.

The regulatory functions and cellular clearance of debris are supported – an anti-inflammatory effect aligning with the antithrombotic mechanisms of APAC (by Aplagon).”

Title: Interactions of Antiplatelet, Anticoagulant (APAC) with C1q and FH modulate complement activation on injured cells

Authors: Juha Kotimaa, Mikel Artero Rezola, Annukka Jouppila, Riitta Lassila, Seppo Meri

Read the Full Article on Blood Vessels, Thrombosis and Hemostasis.

Riitta Lassila: How APAC Impacts the Interplay Between Complement and Coagulation

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