Seema Dawood/LinkedIn
Apr 4, 2026, 16:04
Seema Dawood: Clinical and Laboratory Features of Megaloblastic Anemia
Seema Dawood, Medical Laboratory Technologist at The Aga Khan University Hospital, shared a post on Linkedin:
“Megaloblastic Anemia (Folate, Vitamin B12 Deficiency)
Clinical Features
- Vitamin B12 deficiency: Neurological manifestations due to spinal cord involvement, such as difficulty maintaining posture and paresthesia in hands and feet
- Folate deficiency: No neurological symptoms.
Glossitis.
Laboratory Findings
- Blood smear:
RBC: Increased MCV, Macro-Ovalocytes.
WBC: Hypersegmented Neutrophils. - Serum Cobalamin: For detection of Vitamin B12 deficiency.
- Folate level in RBC and serum: For detection of folate deficiency.”

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